The College GameDay crew makes their picks for Week 1 of the 2022 college football season with Jack Harlow as the special guest.

0:00 Houston vs. UTSA
0:46 Boise State vs. Oregon State
1:31 Louisville vs. Syracuse
2:22 Cincinnati vs. Arkansas
3:20 Utah vs. Florida
4:20 Oregon vs. Georgia
5:08 Notre Dame vs. Ohio State

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